Restoring immune tolerance in neuromyelitis optica: Part II

Neuromyelitis optica spectrum disorder (NMO/SD) and its clinical variants have at their core the loss of immune tolerance to aquaporin-4 and perhaps other autoantigens. The characteristic phenotype is disruption of astrocyte function and demyelination of spinal cord, optic nerves, and particular bra...

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Publicat a:Neurol Neuroimmunol Neuroinflamm
Autors principals: Bar-Or, Amit, Steinman, Larry, Behne, Jacinta M., Benitez-Ribas, Daniel, Chin, Peter S., Clare-Salzler, Michael, Healey, Donald, Kim, James I., Kranz, David M., Lutterotti, Andreas, Martin, Roland, Schippling, Sven, Villoslada, Pablo, Wei, Cheng-Hong, Weiner, Howard L., Zamvil, Scott S., Smith, Terry J., Yeaman, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015540/
https://ncbi.nlm.nih.gov/pubmed/27648464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000277
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