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Rifampicin and anti-hypertensive drugs in chronic kidney disease: Pharmacokinetic interactions and their clinical impact

Patients on dialysis have an increased incidence of tuberculosis (TB). Rifampicin, a first-line antitubercular therapy (ATT) drug, is a potent inducer of hepatic cytochrome P450 (CYP). There is potential for pharmacokinetic interaction between rifampicin and anti-hypertensives that are CYP substrate...

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Bibliographic Details
Published in:Indian J Nephrol
Main Authors: Agrawal, A., Agarwal, S. K., Kaleekal, T., Gupta, Y. K.
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015508/
https://ncbi.nlm.nih.gov/pubmed/27795624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-4065.176145
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