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Purification, characterization, cytotoxicity and anticancer activities of L-asparaginase, anti-colon cancer protein, from the newly isolated alkaliphilic Streptomyces fradiae NEAE-82

L-asparaginase is an important enzyme as therapeutic agents used in combination with other drugs in the treatment of acute lymphoblastic leukemia. A newly isolated actinomycetes strain, Streptomyces sp. NEAE-82, was potentially producing extracellular L-asparaginase, it was identified as Streptomyce...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: El-Naggar, Noura El-Ahmady, Deraz, Sahar F., Soliman, Hoda M., El-Deeb, Nehal M., El-Ewasy, Sara M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015098/
https://ncbi.nlm.nih.gov/pubmed/27605431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32926
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