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Direct Optofluidic Measurement of the Lipid Permeability of Fluoroquinolones

Quantifying drug permeability across lipid membranes is crucial for drug development. In addition, reduced membrane permeability is a leading cause of antibiotic resistance in bacteria, and hence there is a need for new technologies that can quantify antibiotic transport across biological membranes....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cama, Jehangir, Schaich, Michael, Al Nahas, Kareem, Hernández-Ainsa, Silvia, Pagliara, Stefano, Keyser, Ulrich F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015079/
https://ncbi.nlm.nih.gov/pubmed/27604156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32824
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