Alterations of mitochondrial dynamics allow retrograde propagation of locally initiated axonal insults

In chronic neurodegenerative syndromes, neurons progressively die through a generalized retraction pattern triggering retrograde axonal degeneration toward the cell bodies, which molecular mechanisms remain elusive. Recent observations suggest that direct activation of pro-apoptotic signaling in axo...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Lassus, Benjamin, Magifico, Sebastien, Pignon, Sandra, Belenguer, Pascale, Miquel, Marie-Christine, Peyrin, Jean-Michel
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015069/
https://ncbi.nlm.nih.gov/pubmed/27604820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32777
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