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M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner

M2BP (also called 90K) is an interferon-stimulated gene product that is upregulated in HIV-1 infection. A recent study revealed that M2BP reduces the infectivity of HIV-1 by inhibiting the processing of the viral envelope protein. Here we report that in addition to reducing viral infectivity, M2BP i...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Qin, Zhang, Xiaolin, Han, Yuling, Wang, Xinlu, Gao, Guangxia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015019/
https://ncbi.nlm.nih.gov/pubmed/27604950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32736
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