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YAP Subcellular Localization and Hippo Pathway Transcriptome Analysis in Pediatric Hepatocellular Carcinoma

Pediatric hepatocellular carcinoma (HCC) is a rare tumor which is associated with an extremely high mortality rate due to lack of effective chemotherapy. Recently, the Hippo pathway and its transcriptional co-activator Yes-associated protein (YAP) have been shown to play a role in hepatocyte prolife...

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Publicado en:Sci Rep
Main Authors: LaQuaglia, Michael J., Grijalva, James L., Mueller, Kaly A., Perez-Atayde, Antonio R., Kim, Heung Bae, Sadri-Vakili, Ghazaleh, Vakili, Khashayar
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015017/
https://ncbi.nlm.nih.gov/pubmed/27605415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30238
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