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(99m)Tc-Hexamethylpropyleneamine Oxime Imaging for Early Detection of Acute Lung Injury in Rats Exposed to Hyperoxia or Lipopolysaccharide Treatment

(99m)Tc-Hexamethylpropyleneamine oxime (HMPAO) is a clinical single-photon emission computed tomography biomarker of tissue oxidoreductive state. Our objective was to investigate whether HMPAO lung uptake can serve as a pre-clinical marker of lung injury in two well-established rat models of human a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Shock
Hauptverfasser: Audi, Said H., Clough, Anne V., Haworth, Steven T., Medhora, Meetha, Ranji, Mahsa, Densmore, John C., Jacobs, Elizabeth R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014734/
https://ncbi.nlm.nih.gov/pubmed/26974426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000605
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