Analysis of Cancer-targeting Alkylphosphocholine Analog Permeability Characteristics Using a Human Induced Pluripotent Stem Cell Blood-Brain Barrier Model

Cancer-targeting alkylphosphocholine (APC) analogs are being clinically developed for diagnostic imaging, intraoperative visualization, and therapeutic applications. These APC analogs derived from chemically-synthesized phospholipid ethers were identified and optimized for cancer-targeting specifici...

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Udgivet i:Mol Pharm
Main Authors: Clark, Paul A., Alahmad, Abraham J., Qian, Tongcheng, Zhang, Ray R., Wilson, Hannah K., Weichert, Jamey P., Palecek, Sean P., Kuo, John S., Shusta, Eric V.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014630/
https://ncbi.nlm.nih.gov/pubmed/27421304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00441
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