Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori

Helicobacter pylori infects more than 50% of the worldwide population. It is mostly found deep in the gastric mucus lining of the stomach, being a major cause of peptic ulcers and gastric adenocarcinoma. To face the increasing resistance of H. pylori to antibiotics, antimicrobial nucleic acid mimics...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Santos, Rita S, Dakwar, George R, Xiong, Ranhua, Forier, Katrien, Remaut, Katrien, Stremersch, Stephan, Guimarães, Nuno, Fontenete, Sílvia, Wengel, Jesper, Leite, Marina, Figueiredo, Céu, De Smedt, Stefaan C, Braeckmans, Kevin, Azevedo, Nuno F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014538/
https://ncbi.nlm.nih.gov/pubmed/26645765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.46
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