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Application of Peptide Nucleic Acid-based Assays Toward Detection of Somatic Mosaicism

Peptide nucleic acids (PNAs) are synthetic oligonucleotides with many applications. Compared with DNA, PNAs bind their complementary DNA strand with higher specificity and strength, an attribute that can make it an effective polymerase chain reaction clamp. A growing body of work has demonstrated th...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Hong, Christopher S, Yang, Chunzhang, Zhuang, Zhengping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014523/
https://ncbi.nlm.nih.gov/pubmed/27115839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.22
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