High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis

Interferon gamma (IFN-γ) release assays (IGRAs) detect Mycobacterium tuberculosis (Mtb) infection regardless of the active (ATB) or latent (LTBI) forms of tuberculosis (TB). In this study, Mtb-specific T cell response against region of deletion 1 (RD1) antigens were explored by a microbead multiplex...

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Vydáno v:PLoS One
Hlavní autoři: Carrère-Kremer, Séverine, Rubbo, Pierre-Alain, Pisoni, Amandine, Bendriss, Sophie, Marin, Grégory, Peries, Marianne, Bolloré, Karine, Terru, Dominique, Godreuil, Sylvain, Bourdin, Arnaud, Van de Perre, Philippe, Tuaillon, Edouard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014470/
https://ncbi.nlm.nih.gov/pubmed/27603919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162137
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