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The Anti-sigma Factor RsiV Is a Bacterial Receptor for Lysozyme: Co-crystal Structure Determination and Demonstration That Binding of Lysozyme to RsiV Is Required for σ(V) Activation

σ factors provide RNA polymerase with promoter specificity in bacteria. Some σ factors require activation in order to interact with RNA polymerase and transcribe target genes. The Extra-Cytoplasmic Function (ECF) σ factor, σ(V), is encoded by several Gram-positive bacteria and is specifically activa...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Hastie, Jessica L., Williams, Kyle B., Bohr, Lindsey L., Houtman, Jon C., Gakhar, Lokesh, Ellermeier, Craig D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014341/
https://ncbi.nlm.nih.gov/pubmed/27602573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006287
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