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Role of the basic amino acid cluster and Glu-23 in pyrimidine dimer glycosylase activity of T4 endonuclease V.

T4 endonuclease V [endodeoxyribonuclease (pyrimidine dimer); deoxyribonuclease (pyrimidine dimer), EC 3.1.25.1] initiates repair of damaged DNA by hydrolysis of the N-glycosyl bond at the 5' side of a pyrimidine photodimer in double-stranded DNA. To study one of the active sites of T4 endonuclease V...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Doi, T, Recktenwald, A, Karaki, Y, Kikuchi, M, Morikawa, K, Ikehara, M, Inaoka, T, Hori, N, Ohtsuka, E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409651/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9420
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