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Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest.

We have used a genomic library of Candida albicans to transform Saccharomyces cerevisiae and screened for genes that act similarly to dominant negative mutations by interfering with pheromone-mediated cell cycle arrest. Six different plasmids were identified from 2000 transformants; four have been s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Whiteway, M, Dignard, D, Thomas, D Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1409649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.20.9410
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