Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity

Genetic variation in cytochrome P450 2A6 (CYP2A6) gene is the primary contributor to the intraindividual and interindividual differences in nicotine metabolism and has been found to influence smoking intensity. However, no study has evaluated the relationship between CYP2A6 genetic variants and the...

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Publicat a:Carcinogenesis
Autors principals: Park, Sungshim L., Tiirikainen, Maarit I., Patel, Yesha M., Wilkens, Lynne R., Stram, Daniel O., Le Marchand, Loic, Murphy, Sharon E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Original Manuscript
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014092/
https://ncbi.nlm.nih.gov/pubmed/26818358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgw012
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