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Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia

Wilms tumor 1 (WT1) has long been implicated in acute myeloid leukemia. It has been described to be both overexpressed and mutated in different forms of acute myeloid leukemia, and overexpression has been reported to play a prognostic role in this disease. However, the precise mechanism through whic...

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Bibliographic Details
Published in:Haematologica
Main Authors: Rampal, Raajit, Figueroa, Maria E.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013955/
https://ncbi.nlm.nih.gov/pubmed/27252512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.141796
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