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Frequent CTLA4-CD28 gene fusion in diverse types of T-cell lymphoma
CTLA4 and CD28 are co-regulatory receptors with opposite roles in T-cell signaling. By RNA sequencing, we identified a fusion between the two genes from partial gene duplication in a case of angioimmunoblastic T-cell lymphoma. The fusion gene, which codes for the extracellular domain of CTLA4 and th...
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| Publicado no: | Haematologica |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013939/ https://ncbi.nlm.nih.gov/pubmed/26819049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.139253 |
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