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LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs
Motivation: 5-methylcytosine (5mC) is a widely studied epigenetic modification of DNA. The ten-eleven translocation (TET) dioxygenases oxidize 5mC into oxidized methylcytosines (oxi-mCs): 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). DNA methylation modificati...
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| Publicado en: | Bioinformatics |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013920/ https://ncbi.nlm.nih.gov/pubmed/27587669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw468 |
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