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LuxGLM: a probabilistic covariate model for quantification of DNA methylation modifications with complex experimental designs

Motivation: 5-methylcytosine (5mC) is a widely studied epigenetic modification of DNA. The ten-eleven translocation (TET) dioxygenases oxidize 5mC into oxidized methylcytosines (oxi-mCs): 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). DNA methylation modificati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Bioinformatics
Päätekijät: Äijö, Tarmo, Yue, Xiaojing, Rao, Anjana, Lähdesmäki, Harri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013920/
https://ncbi.nlm.nih.gov/pubmed/27587669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw468
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