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Increased expression of readthrough acetylcholinesterase variants in the brains of Alzheimer's disease patients

Alzheimer's disease (AD) is characterized by a decrease in the enzymatic activity of the enzyme acetylcholinesterase (AChE). AChE is expressed as multiple splice variants, which may serve both cholinergic degradative functions and non-cholinergic functions unrelated with their capacity to hydro...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Campanari, Maria-Letizia, Navarrete, Francisco, Ginsberg, Stephen D., Manzanares, Jorge, Sáez-Valero, Javier, García-Ayllón, María-Salud
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013723/
https://ncbi.nlm.nih.gov/pubmed/27258420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-160220
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