Increased risk of type I errors in cluster randomised trials with small or medium numbers of clusters: a review, reanalysis, and simulation study

BACKGROUND: Cluster randomised trials (CRTs) are commonly analysed using mixed-effects models or generalised estimating equations (GEEs). However, these analyses do not always perform well with the small number of clusters typical of most CRTs. They can lead to increased risk of a type I error (find...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Kahan, Brennan C., Forbes, Gordon, Ali, Yunus, Jairath, Vipul, Bremner, Stephen, Harhay, Michael O., Hooper, Richard, Wright, Neil, Eldridge, Sandra M., Leyrat, Clémence
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013635/
https://ncbi.nlm.nih.gov/pubmed/27600609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1571-2
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