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Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
Anti-tumour immune activation by checkpoint inhibitors leads to durable responses in a variety of cancers, but combination approaches are required to extend this benefit beyond a subset of patients. In preclinical models tumour-derived VEGF limits immune cell activity while anti-VEGF augments intra-...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Nat Commun |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5013615/ https://ncbi.nlm.nih.gov/pubmed/27571927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12624 |
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