N-glycan MALDI Imaging Mass Spectrometry on Formalin-Fixed Paraffin-Embedded Tissue Enables the Delineation of Ovarian Cancer Tissues

Ovarian cancer is a fatal gynaecological malignancy in adult women with a five-year overall survival rate of only 30%. Glycomic and glycoproteomic profiling studies have reported extensive protein glycosylation pattern alterations in ovarian cancer. Therefore, spatio-temporal investigation of these...

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Udgivet i:Mol Cell Proteomics
Main Authors: Everest-Dass, Arun V., Briggs, Matthew T., Kaur, Gurjeet, Oehler, Martin K., Hoffmann, Peter, Packer, Nicolle H.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013313/
https://ncbi.nlm.nih.gov/pubmed/27412689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.059816
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