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Vancomycin susceptibility in methicillin-resistant Staphylococcus aureus is mediated by YycHI activation of the WalRK essential two-component regulatory system

The treatment of infections caused by methicillin-resistant Staphylococcus aureus is complicated by the emergence of strains with intermediate-level resistance to vancomycin (termed VISA). We have characterised a molecular pathway involved in the in vivo evolution of VISA mediated by the regulatory...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Cameron, David R., Jiang, Jhih-Hang, Kostoulias, Xenia, Foxwell, Daniel J., Peleg, Anton Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013275/
https://ncbi.nlm.nih.gov/pubmed/27600558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30823
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