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Unexpected behavior of the heaviest halogen astatine in the nucleophilic substitution of aryliodonium salts

Aryliodonium salts have become precursors of choice for the synthesis of (18)F-labelled tracers for nuclear imaging. However little is known on the reactivity of these precursors with heavy halogenides, i.e. radioiodide and astatide at the radiotracer scale. Herein, we report the first comparative s...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Guérard, François, Lee, Yong-Sok, Baidoo, Kwamena, Gestin, Jean-François, Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013196/
https://ncbi.nlm.nih.gov/pubmed/27305065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201600922
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