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Diphtheria Toxin-Induced Cell Death Triggers Wnt-Dependent Hair Cell Regeneration in Neonatal Mice

Cochlear hair cells (HCs), the sensory cells that respond to sound, do not regenerate after damage in adult mammals, and their loss is a major cause of deafness. Here we show that HC regeneration in newborn mouse ears occurred spontaneously when the original cells were ablated by treatment with diph...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Hu, Lingxiang, Lu, Jingrong, Chiang, Hao, Wu, Hao, Edge, Albert S. B., Shi, Fuxin
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013193/
https://ncbi.nlm.nih.gov/pubmed/27605621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2447-15.2016
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