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Spreading depolarization in the brain of Drosophila is induced by inhibition of the Na(+)/K(+)-ATPase and mitigated by a decrease in activity of protein kinase G

Spreading depolarization (SD) is characterized by a massive redistribution of ions accompanied by an arrest in electrical activity that slowly propagates through neural tissue. It has been implicated in numerous human pathologies, including migraine, stroke, and traumatic brain injury, and thus the...

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Bibliografische gegevens
Gepubliceerd in:J Neurophysiol
Hoofdauteurs: Spong, Kristin E., Rodríguez, Esteban C., Robertson, R. Meldrum
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013169/
https://ncbi.nlm.nih.gov/pubmed/27358319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00353.2016
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