Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward

PURPOSE: The use of radiographic response as the primary end point in phase II osteosarcoma trials may limit optimal detection of treatment response because of the calcified tumor matrix. We performed this study to determine if time to progression could be used as an end point for subsequent studies...

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Dettagli Bibliografici
Pubblicato in:J Clin Oncol
Autori principali: Lagmay, Joanne P., Krailo, Mark D., Dang, Ha, Kim, AeRang, Hawkins, Douglas S., Beaty, Orren, Widemann, Brigitte C., Zwerdling, Theodore, Bomgaars, Lisa, Langevin, Anne-Marie, Grier, Holcombe E., Weigel, Brenda, Blaney, Susan M., Gorlick, Richard, Janeway, Katherine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2016
Soggetti:
ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012712/
https://ncbi.nlm.nih.gov/pubmed/27400942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.65.5381
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