Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl Cellulose on Their Absorption

The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tanaka, Akiko, Furubayashi, Tomoyuki, Matsushita, Akifumi, Inoue, Daisuke, Kimura, Shunsuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012702/
https://ncbi.nlm.nih.gov/pubmed/27598527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159150
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