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Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl Cellulose on Their Absorption

The nasal absorption of macromolecules from powder formulations and the effect of sodium carboxymethyl cellulose (CMC-Na) as a pharmaceutical excipient on their absorption were studied. Model macromolecules were fluorescein isothiocyanate-labeled dextran (average molecular weight of 4.4kDa, FD4) and...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Tanaka, Akiko, Furubayashi, Tomoyuki, Matsushita, Akifumi, Inoue, Daisuke, Kimura, Shunsuke, Katsumi, Hidemasa, Sakane, Toshiyasu, Yamamoto, Akira
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012702/
https://ncbi.nlm.nih.gov/pubmed/27598527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159150
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