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Everolimus in the management of metastatic renal cell carcinoma: an evidence-based review of its place in therapy
INTRODUCTION: Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, and its pathogenesis is strictly related to altered cellular response to hypoxia, in which mTOR signaling pathway is implicated. Everolimus, an mTOR serine/threonine kinase inhibitor, represents a therapeuti...
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| Published in: | Core Evid |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012611/ https://ncbi.nlm.nih.gov/pubmed/27621699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CE.S98687 |
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