Axonopathy in the Central Nervous System Is the Hallmark of Mice with a Novel Intragenic Null Mutation of Dystonin

Dystonia musculorum is a neurodegenerative disorder caused by a mutation in the dystonin gene. It has been described in mice and humans where it is called hereditary sensory autonomic neuropathy. Mutated mice show severe movement disorders and die at the age of 3–4 weeks. This study describes the di...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Seehusen, Frauke, Kiel, Kirsten, Jottini, Stefano, Wohlsein, Peter, Habierski, Andre, Seibel, Katharina, Vogel, Tanja, Urlaub, Henning, Kollmar, Martin, Baumgärtner, Wolfgang, Teichmann, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012385/
https://ncbi.nlm.nih.gov/pubmed/27401753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.186932
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