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The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase

Interactions of proline-rich motifs with SH3 domains are present in signal transduction and other important cell processes. Analysis of structural and thermodynamic data suggest a relevant role of water molecules in these protein–protein interactions. To determine whether or not the SH3 domain of th...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Camara-Artigas, Ana, Ortiz-Salmeron, Emilia, Andujar-Sánchez, Montserrrat, Bacarizo, Julio, Martin-Garcia, Jose Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012211/
https://ncbi.nlm.nih.gov/pubmed/27599862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16012310
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