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Exploring complex cellular phenotypes and model-guided strain design with a novel genome-scale metabolic model of Clostridium thermocellum DSM 1313 implementing an adjustable cellulosome

BACKGROUND: Clostridium thermocellum is a gram-positive thermophile that can directly convert lignocellulosic material into biofuels. The metabolism of C. thermocellum contains many branches and redundancies which limit biofuel production, and typical genetic techniques are time-consuming. Further,...

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Dettagli Bibliografici
Pubblicato in:Biotechnol Biofuels
Autori principali: Thompson, R. Adam, Dahal, Sanjeev, Garcia, Sergio, Nookaew, Intawat, Trinh, Cong T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012057/
https://ncbi.nlm.nih.gov/pubmed/27602057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-016-0607-x
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