Exploring complex cellular phenotypes and model-guided strain design with a novel genome-scale metabolic model of Clostridium thermocellum DSM 1313 implementing an adjustable cellulosome

BACKGROUND: Clostridium thermocellum is a gram-positive thermophile that can directly convert lignocellulosic material into biofuels. The metabolism of C. thermocellum contains many branches and redundancies which limit biofuel production, and typical genetic techniques are time-consuming. Further,...

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Bibliografiske detaljer
Udgivet i:Biotechnol Biofuels
Main Authors: Thompson, R. Adam, Dahal, Sanjeev, Garcia, Sergio, Nookaew, Intawat, Trinh, Cong T.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012057/
https://ncbi.nlm.nih.gov/pubmed/27602057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-016-0607-x
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