Association of polymorphisms in genes of factors involved in regulation of splicing of cystic fibrosis transmembrane conductance regulator mRNA with acute respiratory distress syndrome in children with pneumonia

BACKGROUND: Previous work has demonstrated a strong association between lung injury in African American children with pneumonia and a polymorphic (TG)(m)T(n) region in cystic fibrosis transmembrane conductance (CFTR) involved in the generation of a nonfunctional CFTR protein lacking exon 9. A number...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Perez-Marques, Francesca, Simpson, Pippa, Yan, Ke, Quasney, Michael W., Halligan, Nadine, Merchant, Daniel, Dahmer, Mary K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011993/
https://ncbi.nlm.nih.gov/pubmed/27596159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-016-1454-7
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