Spontaneous onset and transplant models of the Vk*MYC mouse show immunological sequelae comparable to human multiple myeloma

BACKGROUND: The Vk*MYC transgenic and transplant mouse models of multiple myeloma (MM) are well established as a research tool for anti-myeloma drug discovery. However, little is known of the immune response in these models. Understanding the immunological relevance of these models is of increasing...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Cooke, Rachel E., Gherardin, Nicholas A., Harrison, Simon J., Quach, Hang, Godfrey, Dale I., Prince, Miles, Koldej, Rachel, Ritchie, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011922/
https://ncbi.nlm.nih.gov/pubmed/27599546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0994-6
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