Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion

INTRODUCTION: Treprostinil diethanolamine is an innovative salt form of the prostacyclin analogue, treprostinil sodium, developed as an oral sustained release (SR) osmotic tablet. The availability of a formulation permitting convenient systemic delivery might have applicability to scleroderma vascul...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Shah, Ami A, Schiopu, Elena, Hummers, Laura K, Wade, Michael, Phillips, Kristine, Anderson, Cynthia, Wise, Robert, Boin, Francesco, Seibold, James R, Wigley, Fredrick, Rollins, Kristan D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011881/
https://ncbi.nlm.nih.gov/pubmed/23597147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4216
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