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ACT‐ONE ‐ ACTION at last on cancer cachexia by adapting a novel action beta‐blocker
Novel action beta‐blockers combine many different pharmacological effects. The espindolol exhibits effects through β and central 5‐HT1α receptors to demonstrate pro‐anabolic, anti‐catabolic, and appetite‐stimulating actions. In the ACT‐ONE trial, espindolol reversed weight loss and improved handgrip...
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| Pubblicato in: | J Cachexia Sarcopenia Muscle |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5011815/ https://ncbi.nlm.nih.gov/pubmed/27625919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12136 |
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