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KIF3A binds to β-arrestin for suppressing Wnt/β-catenin signalling independently of primary cilia in lung cancer

Aberrant Wnt/β-catenin signalling is implicated in the progression of several human cancers, including non-small cell lung cancer (NSCLC). However, mutations in Wnt/β-catenin pathway components are uncommon in NSCLC, and their epigenetic control remains unclear. Here, we show that KIF3A, a member of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Minsuh, Suh, Young-Ah, Oh, Ju-Hee, Lee, Bo Ra, Kim, Joon, Jang, Se Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011747/
https://ncbi.nlm.nih.gov/pubmed/27596264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32770
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