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Up-regulation of miR-370-3p restores glioblastoma multiforme sensitivity to temozolomide by influencing MGMT expression

MicroRNAs (miRNA) are believed to play an important role in glioblastoma multiforme (GBM)chemotherapy. Our study aims to investigate potential miRNA biomarkers in GBM. Sixty GBM patients, which were given temozolomide (TMZ) chemotherapy and recurrent radiotherapy, were recruited. miRNA array was per...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gao, Yong-tao, Chen, Xiao-bing, Liu, Hong-lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011744/
https://ncbi.nlm.nih.gov/pubmed/27595933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32972
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