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Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice

Current therapies for multiple sclerosis (MS) reduce the frequency of relapses by modulating adaptive immune responses but fail to limit the irreversible neurodegeneration driving progressive disability. Experimental autoimmune encephalomyelitis (EAE) in Biozzi ABH mice recapitulates clinical featur...

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Bibliographic Details
Published in:Immunology
Main Authors: Peferoen, Laura A. N., Breur, Marjolein, van de Berg, Sarah, Peferoen‐Baert, Regina, Boddeke, Erik H. W. G. M., van der Valk, Paul, Pryce, Gareth, van Noort, Johannes M., Baker, David, Amor, Sandra
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011681/
https://ncbi.nlm.nih.gov/pubmed/27388634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12644
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