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Ageing and recurrent episodes of neuroinflammation promote progressive experimental autoimmune encephalomyelitis in Biozzi ABH mice

Current therapies for multiple sclerosis (MS) reduce the frequency of relapses by modulating adaptive immune responses but fail to limit the irreversible neurodegeneration driving progressive disability. Experimental autoimmune encephalomyelitis (EAE) in Biozzi ABH mice recapitulates clinical featur...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Peferoen, Laura A. N., Breur, Marjolein, van de Berg, Sarah, Peferoen‐Baert, Regina, Boddeke, Erik H. W. G. M., van der Valk, Paul, Pryce, Gareth, van Noort, Johannes M., Baker, David, Amor, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011681/
https://ncbi.nlm.nih.gov/pubmed/27388634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12644
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