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CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.

T-cell antigens including CD2, CD4, CD6, CD8, and CD28 serve as coreceptors with the T-cell receptor (TCR)/CD3 complex in control of T-cell growth. The molecular basis by which these antigens fulfill this role has remained a major issue. An initial clue to this question came with our finding that th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Burgess, K E, Yamamoto, M, Prasad, K V, Rudd, C E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1384049/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.19.9311
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