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Suppression of liver Apo E secretion leads to HDL/cholesterol immaturity in rats administered ethinylestradiol

Ethinylestradiol (EE), a main component of the combined oral contraceptive pill, is associated with an increased risk of arterial diseases. However, the toxicity mechanism of EE is poorly understood. In this study, we found that the exposure to EE reduced the serum apolipoprotein E (Apo E) level and...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Yamaguchi, Kosuke, Ishii, Mariko, Maeda, Naoyuki, Iwano, Hidetomo, Yokota, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011491/
https://ncbi.nlm.nih.gov/pubmed/27642556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12098
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