Plasmacytoid dendritic cells and type 1 interferon promote peripheral expansion of forkhead box protein 3(+) regulatory T cells specific for the ubiquitous RNA‐binding nuclear antigen La/Sjögren's syndrome (SS)‐B

RNA‐binding nuclear antigens are a major class of self‐antigen to which immune tolerance is lost in rheumatic diseases. Serological tolerance to one such antigen, La/Sjögren's syndrome (SS)‐B (La), is controlled by CD4(+) T cells. This study investigated peripheral tolerance to human La (hLa) b...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Pan, Z.‐J., Horton, C. G., Lawrence, C., Farris, A. D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011359/
https://ncbi.nlm.nih.gov/pubmed/27227559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12817
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