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The ETS family transcription factors Etv5 and PU.1 function in parallel to promote Th9 cell development

The IL-9-secreting Th9 subset of CD4 T helper cells develop in response to an environment containing IL-4 and TGFβ, promoting allergic disease, autoimmunity, and resistance to pathogens. We previously identified a requirement for the ETS family transcription factor PU.1 in Th9 development. In this r...

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Vydáno v:J Immunol
Hlavní autoři: Koh, Byunghee, Hufford, Matthew M, Pham, Duy, Olson, Matthew R., Wu, Tong, Jabeen, Rukhsana, Sun, Xin, Kaplan, Mark H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010937/
https://ncbi.nlm.nih.gov/pubmed/27496971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502383
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