Does the preclinical evidence for functional remyelination following engraftment into the injured spinal cord support progression to clinical trials?

This article reviews all historical literature in which rodent-derived myelinating cells have been engrafted into the contused adult rodent spinal cord. From 2,500 initial PubMed citations identified, human cells grafts, bone mesenchymal stem cells, olfactory ensheathing cells, non-myelinating cell...

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Pubblicato in:Exp Neurol
Autori principali: Myers, Scott A., Bankston, Andrew N., Burke, Darlene A., Ohri, Sujata Saraswat, Whittemore, Scott R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010929/
https://ncbi.nlm.nih.gov/pubmed/27085393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.04.009
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