AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

We isolated cDNA clones containing the entire coding region of the putative oncogene AKT2. Sequence analysis and in vitro translation demonstrated that AKT2 encodes a 56-kDa protein with homology to serine/threonine kinases; moreover, this protein contains a Src homology 2-like domain. AKT2 was show...

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Main Authors: Cheng, J Q, Godwin, A K, Bellacosa, A, Taguchi, T, Franke, T F, Hamilton, T C, Tsichlis, P N, Testa, J R
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC50107/
https://ncbi.nlm.nih.gov/pubmed/1409633
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