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The WASF3-NCKAP1-CYFIP1 complex is essential for breast cancer metastasis

Inactivation of the WASF3 gene suppresses invasion and metastasis of breast cancer cells. WASF3 function is regulated through a protein complex that includes the NCKAP1 and CYFIP1 proteins. Here we report that silencing NCKAP1 destabilizes the WASF3 complex, resulting in a suppression of the invasiv...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Teng, Yong, Qin, Haiyan, Bahassan, Abdulaziz, Bendzunas, N George, Kennedy, Eileen J, Cowell, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010469/
https://ncbi.nlm.nih.gov/pubmed/27432794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0562
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