Adjuvant Oral Uracil-Tegafur with Leucovorin for Colorectal Cancer Liver Metastases: A Randomized Controlled Trial

BACKGROUND: The high recurrence rate after surgery for colorectal cancer liver metastasis (CLM) remains a crucial problem. The aim of this trial was to evaluate the efficacy of adjuvant therapy with uracil-tegafur and leucovorin (UFT/LV). METHODS: In the multicenter, open-label, phase III trial, pat...

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Publicat a:PLoS One
Autors principals: Hasegawa, Kiyoshi, Saiura, Akio, Takayama, Tadatoshi, Miyagawa, Shinichi, Yamamoto, Junji, Ijichi, Masayoshi, Teruya, Masanori, Yoshimi, Fuyo, Kawasaki, Seiji, Koyama, Hiroto, Oba, Masaru, Takahashi, Michiro, Mizunuma, Nobuyuki, Matsuyama, Yutaka, Watanabe, Toshiaki, Makuuchi, Masatoshi, Kokudo, Norihiro
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5010179/
https://ncbi.nlm.nih.gov/pubmed/27588959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162400
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